Neurofilament Levels Are Reflecting the Loss of Presynaptic Dopamine Receptors in Movement Disorders

Neurofilament Levels Are Reflecting the Loss of Presynaptic Dopamine Receptors in Movement Disorders

Aims: Neurofilament light chain (NfL) and phosphorylated neurofilament heavy chain (pNfH) are biomarkers for neuroaxonal damage. We assessed whether NfL and other biomarker levels in the CSF are correlated to the loss of presynaptic dopamine transporters in neurons as detected with dopamine transpor...

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Bibliographic Details
Main Authors: Elena Diekämper, Britta Brix, Winfried Stöcker, Stefan Vielhaber, Imke Galazky, Michael C. Kreissl, Philipp Genseke, Emrah Düzel, Péter Körtvelyessy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Neuroscience
Subjects:
neurofilament light chain
movement disorders
DaTscan
Parkinson’s Disease
CSF
alpha-synuclein
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.690013/full

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https://www.frontiersin.org/articles/10.3389/fnins.2021.690013/full

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