Random walk informed heterogeneity detection reveals how the lymph node conduit network influences T cells collective exploration behavior.

Random walks on networks are widely used to model stochastic processes such as search strategies, transportation problems or disease propagation. A prominent example of such process is the dynamics of naive T cells within the lymph node while they are scanning for antigens. The observed T cells traj...

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Bibliographic Details
Main Authors: Solène Song, Malek Senoussi, Paul Escande, Paul Villoutreix
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1011168