A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO2

Structurally diverse thiazoles with electron-donating and electron-withdrawing groups were conveniently synthesized through manganese dioxide (MnO2) oxidation of the corresponding thiazolines. The effect of substitution at the 2- and 4-positions was investigated. The desired thiazoles with aryl or v...

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Bibliographic Details
Main Authors: Bin Fu, Yan-Bo Yu, Hong-Liang Chen, Xin-Zheng Chen, Li-Yi Wang
Format: Article
Language:English
Published: MDPI AG 2009-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/14/12/4858/