Combination of cafeteria diet with intraperitoneally streptozotocin in rats. A type-2 diabetes model

Combination of cafeteria diet with intraperitoneally streptozotocin in rats. A type-2 diabetes model

ABSTRACT Purpose To develop a model of induction of type-2 diabetes (DM2) by combining low doses of streptozotocin (STZ) and a cafeteria diet. Methods Forty male Wistar rats (200 g) were allocated into four groups: control (non-diabetic, n = 10); STZ 30 mg/kg (diabetic, n = 10); STZ 35 mg/kg (diab...

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Bibliographic Details
Main Authors: Mirelly Marques Romeiro Santos, Andressa Carolina Farias Pereira Subtil Cavalcante, Luane Aparecida do Amaral, Gabriel Henrique Oliveira de Souza, Bárbara Suzuki dos Santos, Luciane Candeloro Portugal, Felipe Franscisco Bittencourt Junior, Thiago Troquez, Bruna Paola Murino Rafacho, Priscila Aiko Hiane, Elisvânia Freitas dos Santos
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2021-08-01
Series:Acta Cirúrgica Brasileira
Subjects:
Liver
Hyperglycemia
Body Weight
Pancreas
Models
Animal
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021000700200&tlng=en

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