Hypomethylation-associated up-regulation of TCF3 expression and recurrence in stage II and III colorectal cancer.

BACKGROUND AND OBJECTIVES: Transcription factor 3 (TCF3) implicates Wnt signaling pathway and regulates E-cadherin expression, which is involved in aggressiveness of tumors. This study aims to investigate the role of TCF3 in predicting prognosis of patients with stage II and III colorectal cancer (C...

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Bibliographic Details
Main Authors: Chunxiang Li, Sanjun Cai, Xishan Wang, Zheng Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4222969?pdf=render