Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer

Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer

Aberrant activation of epithelial-mesenchymal transition (EMT) in carcinoma cells contributes to increased migration and invasion, metastasis, drug resistance, and tumor-initiating capacity. EMT is not always a binary process; rather, cells...

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Bibliographic Details
Main Authors: Mohit Kumar Jolly, Bogdan-Tiberius Preca, Satyendra C. Tripathi, Dongya Jia, Jason T. George, Samir M. Hanash, Thomas Brabletz, Marc P. Stemmler, Jochen Maurer, Herbert Levine
Format: Article
Language:English
Published: AIP Publishing LLC 2018-09-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/1.5024874

Internet

http://dx.doi.org/10.1063/1.5024874

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