Pin1 colocalization with phosphorylated tau in Alzheimer's disease and other tauopathies

Pin1 colocalization with phosphorylated tau in Alzheimer's disease and other tauopathies

Pin1, a peptidyl-prolyl isomerase binds to mitotic serine or threonine phosphoproteins. In Alzheimer's disease (AD) evidence points to the reactivation of mitosis in vulnerable neurons. Tangles composed of hyperphosphorylated tau contain phosphorylated Thr231 (pThr231 tau), which occurs to a gr...

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Bibliográfalaš dieđut
Váldodahkkit: Pankajavalli Ramakrishnan, Dennis W Dickson, Peter Davies
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Elsevier 2003-11-01
Ráidu:Neurobiology of Disease
Fáttát:
Alzheimer's disease
Neurodegeneration
Pin1
Tau
Tauopathies
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S0969996103001098

Interneahtta

http://www.sciencedirect.com/science/article/pii/S0969996103001098

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