Copper-catalyzed remote C(sp 3)–H azidation and oxidative trifluoromethylation of benzohydrazides

Functionalization of carbon radicals formed via 1,5-hydrogen atom transfer of amidyl radicals is an underdeveloped protocol for remote C–H functionalization. Here, the authors report a Cu-catalyzed γ-azidation and oxidative δ-trifluoromethylation of benzohydrazides for the synthesis of more function...

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Bibliographic Details
Main Authors: Xu Bao, Qian Wang, Jieping Zhu
Format: Article
Language:English
Published: Nature Portfolio 2019-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08741-w