Oxidative Distress Induces Wnt/β-Catenin Pathway Modulation in Colorectal Cancer Cells: Perspectives on APC Retained Functions

Oxidative Distress Induces Wnt/β-Catenin Pathway Modulation in Colorectal Cancer Cells: Perspectives on APC Retained Functions

Colorectal cancer (CRC) is a multistep process that arises in the colic tissue microenvironment. Oxidative stress plays a role in mediating CRC cell survival and progression, as well as promoting resistance to therapies. CRC progression is associated with Wnt/β-Catenin signaling dysregulation and lo...

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Bibliographic Details
Main Authors: Teresa Catalano, Emira D’Amico, Carmelo Moscatello, Maria Carmela Di Marcantonio, Alessio Ferrone, Giuseppina Bologna, Federico Selvaggi, Paola Lanuti, Roberto Cotellese, Maria Cristina Curia, Rossano Lattanzio, Gitana Maria Aceto
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
colorectal cancer
oxidative stress
Wnt/β-Catenin
APC
gene expression
protein expression
Online Access:https://www.mdpi.com/2072-6694/13/23/6045

Internet

https://www.mdpi.com/2072-6694/13/23/6045

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