Analysis of epigenetic factors in mouse embryonic neural stem cells exposed to hyperglycemia.

Analysis of epigenetic factors in mouse embryonic neural stem cells exposed to hyperglycemia.

BACKGROUND: Maternal diabetes alters gene expression leading to neural tube defects (NTDs) in the developing brain. The mechanistic pathways that deregulate the gene expression remain unknown. It is hypothesized that exposure of neural stem cells (NSCs) to high glucose/hyperglycemia results in activ...

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Bibliographic Details
Main Authors: Sukanya Shyamasundar, Shweta P Jadhav, Boon Huat Bay, Samuel Sam Wah Tay, S Dinesh Kumar, Danny Rangasamy, S Thameem Dheen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3679101?pdf=render

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http://europepmc.org/articles/PMC3679101?pdf=render

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