Post-transcriptional regulation of amyloid precursor protein by microRNAs and RNA binding proteins
Amyloid Precursor Protein (APP) and its proteolytic product amyloid beta (Αβ) are critical in the pathogenesis of Alzheimer’s Disease (AD). APP gene duplication and transcriptional upregulation are linked to AD. In addition, normal levels of APP appear to be required for some physiological functions...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2010-11-01
|
| Series: | Communicative & Integrative Biology |
| Online Access: | https://www.tandfonline.com/doi/10.4161/cib.3.6.13172 |