Alteration of AP-endonuclease1 expression in curcumin-treated fibrotic rats

Alteration of AP-endonuclease1 expression in curcumin-treated fibrotic rats

Background. Apurinic/apyrimidinic endonuclease1/ redox factor-1 (APE1/Ref-1) is a multifunctional protein involved in DNA base excision repair and redox regulation of many transcription factors. It is an important pro-survival protein activated in response to oxidative stress. Increased level of thi...

Full description

Bibliographic Details
Main Authors: Ahmad R. Bassiouny, Amira Zaky, Faten Fawky, Kamal M. Kandeel
Format: Article
Language:English
Published: Elsevier 2011-10-01
Series:Annals of Hepatology
Subjects:
Apurinic/apyrimidinic endonuclease 1
Hepatic stellate cells
Curcumin
Tumor necrosis factor-α (TNF-α)
Nuclear factor-kappaB (Nf-κB)
Transforming growth factor-β (TGF-β)
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119315212

Internet

http://www.sciencedirect.com/science/article/pii/S1665268119315212

Similar Items