Enhanced Thrombotic Responses Are Associated With Striatin Deficiency and Aldosterone

Background In addition to its role on blood pressure, aldosterone (ALDO) also affects the hemostatic system leading to increased experimental thrombosis. Striatin is an intermediate in the rapid, nongenomic actions of ALDO. Striatin heterozygote knockout (Strn+/‐) mice have salt sensitivity of blood...

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Bibliographic Details
Main Authors: Anna Gromotowicz‐Poplawska, Robert Flaumenhaft, Shadi K. Gholami, Glenn Merrill‐Skoloff, Ewa Chabielska, Gordon H. Williams, Jose R. Romero
Format: Article
Language:English
Published: Wiley 2021-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.022975