Cathepsin B and Plasma Kallikrein Are Reliable Biomarkers to Discriminate Clinically Significant Hepatic Fibrosis in Patients with Chronic Hepatitis-C Infection

Cathepsin B and Plasma Kallikrein Are Reliable Biomarkers to Discriminate Clinically Significant Hepatic Fibrosis in Patients with Chronic Hepatitis-C Infection

We aimed to determine the biomarker performance of the proteolytic enzymes cathepsin B (Cat B) and plasma kallikrein (PKa) and transforming growth factor (TGF)-β to detect hepatic fibrosis (HF) in chronic hepatitis C (CHC) patients. We studied 53 CHC patients and 71 healthy controls (HCs). Hepatic-d...

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Bibliographic Details
Main Authors: Alexia de Cassia Oliveira Zanelatto, Gilmar de Souza Lacerda, Camila de Melo Accardo, Natalia Fonseca do Rosário, Andréa Alice da Silva, Guacyara Motta, Ivarne Luis dos Santos Tersariol, Analucia Rampazzo Xavier
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Microorganisms
Subjects:
HCV
hepatic fibrosis
chronic hepatitis C
plasma kallikrein
cathepsin B
TGF-β
Online Access:https://www.mdpi.com/2076-2607/10/9/1769

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https://www.mdpi.com/2076-2607/10/9/1769

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