Unveiling the interplay between mutational signatures and tumor microenvironment: a pan-cancer analysis

BackgroundWhile recent studies have separately explored mutational signatures and the tumor microenvironment (TME), there is limited research on the associations of both factors in a pan-cancer context.Materials and methodsWe performed a pan-cancer analysis of over 8,000 tumor samples from The Cance...

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Bibliographic Details
Main Authors: Li-Zhi Luo, Sheng Li, Chen Wei, Jiao Ma, Li-Mei Qian, Yan-Xing Chen, Shi-Xiang Wang, Qi Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1186357/full