Divergent Importance of Chronobiological Considerations in High- and Low-dose Melatonin Therapies

Melatonin has been used preclinically and clinically for different purposes. Some applications are related to readjustment of circadian oscillators, others use doses that exceed the saturation of melatonin receptors MT<sub>1</sub> and MT<sub>2</sub> and are unsuitable for chr...

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Bibliographic Details
Main Author: Rüdiger Hardeland
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Diseases
Subjects:
Online Access:https://www.mdpi.com/2079-9721/9/1/18