Modulatory Effects of Atractylodin and β-Eudesmol on Human Cytochrome P450 Enzymes: Potential Drug-Drug Interactions

Atractylodin and β-eudesmol, the major bioactive compounds in <i>Atractylodes lancea</i>, are promising candidates for anti-cholangiocarcinoma. The inhibitory effects of both compounds on human rCYP1A2, rCYP2C9, rCYP2C19, rCYP2D6 and rCYP3A4 enzymes were investigated using luminogenic CY...

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Bibliographic Details
Main Authors: Artitaya Thiengsusuk, Tullayakorn Plengsuriyakarn, Kesara Na-Bangchang
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/7/3140