Role of <i>IL6R</i> Genetic Variants in Predicting Response to Tocilizumab in Patients with Rheumatoid Arthritis

Role of <i>IL6R</i> Genetic Variants in Predicting Response to Tocilizumab in Patients with Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a prevalent autoimmune disease characterized by chronic arthritis that may lead to irreversible joint damage and significant disability. Patients with RA are commonly treated with Tocilizumab (TCZ), an IL-6 receptor (IL-6R) antagonist, but many patients refractorily resp...

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Bibliographic Details
Main Authors: Luis Sainz, Pau Riera, Patricia Moya, Sara Bernal, Jordi Casademont, Cesar Díaz-Torné, Ana Milena Millán, Hye Sang Park, Adriana Lasa, Héctor Corominas
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
<i>IL6R</i>
genetic variants
tocilizumab
rheumatoid arthritis
predictive factors
Online Access:https://www.mdpi.com/1999-4923/14/9/1942

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https://www.mdpi.com/1999-4923/14/9/1942

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