DEGAS: de novo discovery of dysregulated pathways in human diseases.

BACKGROUND: Molecular studies of the human disease transcriptome typically involve a search for genes whose expression is significantly dysregulated in sick individuals compared to healthy controls. Recent studies have found that only a small number of the genes in human disease-related pathways sho...

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Bibliographic Details
Main Authors: Igor Ulitsky, Akshay Krishnamurthy, Richard M Karp, Ron Shamir
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2957424?pdf=render