Picomolar-sensitive β-amyloid fibril fluorophores by tailoring the hydrophobicity of biannulated π-elongated dioxaborine-dyes

The pathological origin of Alzheimer's disease (AD) is still shrouded in mystery, despite intensive worldwide research efforts. The selective visualization of β-amyloid (Aβ), the most abundant proteinaceous deposit in AD, is pivotal to reveal AD pathology. To date, several small-molecule fluoro...

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Bibliographic Details
Main Authors: Jusung An, Peter Verwilst, Hira Aziz, Jinwoo Shin, Sungsu Lim, Ilwha Kim, Yun Kyung Kim, Jong Seung Kim
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-07-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2100520X