Single-nucleus resolution mapping of the adult C. elegans and its application to elucidate inter- and trans-generational response to alcohol

Summary: Single-cell transcriptomic platforms provide an opportunity to map an organism’s response to environmental cues with high resolution. Here, we applied single-nucleus RNA sequencing (snRNA-seq) to establish the tissue and cell type-resolved transcriptome of the adult C. elegans and character...

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Bibliographic Details
Main Authors: Lisa Truong, Yen-Wei Chen, Rio Barrere-Cain, Max T. Levenson, Karissa Shuck, Wen Xiao, Eduardo da Veiga Beltrame, Blake Panter, Ella Reich, Paul W. Sternberg, Xia Yang, Patrick Allard
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723005466