Spectroscopic and in silico approach to probe the binding interactions of irbesartan and human serum albumin

Spectroscopic and in silico approach to probe the binding interactions of irbesartan and human serum albumin

Objective: The free and active concentration of drugs and thereby their pharmacokinetic properties are controlled by their binding to human serum albumin (HSA) protein. Irbesartan (IRB), an antihypertensive drug was aimed to be investigated in terms of its binding interactions with different sites o...

Full description

Bibliographic Details
Main Authors: Asim Najmi, Mohammed Albratty, Hassan Ahmad Alhazmi, Neelaveni Thangavel, Md Shamsher Alam, Waquar Ahsan, Sadique Akhtar Javed, Ismail Adam Arbab, Karam Ahmed El-Sharkawy
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Journal of King Saud University: Science
Subjects:
Binding interactions
Human Serum Albumin
Irbesartan
Molecular Docking
Spectroscopic Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364722000568

Internet

http://www.sciencedirect.com/science/article/pii/S1018364722000568

Similar Items