Tumor-Associated Fibronectin Targeted Liposomal Nanoplatform for Cyclophilin A siRNA Delivery and Targeted Malignant Glioblastoma Therapy

Tumor-Associated Fibronectin Targeted Liposomal Nanoplatform for Cyclophilin A siRNA Delivery and Targeted Malignant Glioblastoma Therapy

Malignant glioblastoma (GBM) is the most aggressive brain cancer that has a very low survival rate. With the rapid development of nanotechnology in the past few decades, the use of nanoparticles (NPs) for nucleic acid delivery is expected to have a revolutionary impact on GBM therapy. However, clini...

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Bibliographic Details
Main Authors: Phei Er Saw, Ao Zhang, Yan Nie, Lei Zhang, Yingjie Xu, Xiaoding Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
nanoparticle
aptide
siRNA
targeted delivery
glioblastoma
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01194/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01194/full

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