Mitochondrial dependent pathway is involved in the protective effects of carboxymethylated chitosan on nitric oxide-induced apoptosis in chondrocytes

Mitochondrial dependent pathway is involved in the protective effects of carboxymethylated chitosan on nitric oxide-induced apoptosis in chondrocytes

Abstract Background Chondrocyte apoptosis activated by the mitochondrial dependent pathway serves a crucial role in cartilage degeneration of osteoarthritis (OA). In the present study, the protective effects of CMCS against sodium nitroprusside (SNP)-induced chondrocyte apoptosis were evaluated and...

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Bibliographic Details
Main Authors: Bin He, Fei Wu, Xiaohai Li, Yang Liu, Li Fan, Haohuan Li
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Carboxymethylated chitosan
Osteoarthritis
Chondrocytes
Apoptosis
Online Access:https://doi.org/10.1186/s12906-019-2808-x

Internet

https://doi.org/10.1186/s12906-019-2808-x

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