Recent Advances in Target Characterization and Identification by Photoaffinity Probes

Recent Advances in Target Characterization and Identification by Photoaffinity Probes

Target identification of biologically active molecules such as natural products, synthetic small molecules, peptides, and oligonucleotides mainly relies on affinity chromatography, activity-based probes, or photoaffinity labeling (PAL). Amongst them, activity-based probes and PAL have offered great...

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Bibliographic Details
Main Authors: Sang J. Chung, Jitapa Sumranjit
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Molecules
Subjects:
protein target identification
photoaffinity labeling
affinity chromatography
chemical proteomics
photo-crosslinking
bioorthogonal ligation
two step labeling
click chemistry
Online Access:http://www.mdpi.com/1420-3049/18/9/10425

Internet

http://www.mdpi.com/1420-3049/18/9/10425

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