Poly-Lysine Dendritic Nanocarrier to Target Epidermal Growth Factor Receptor Overexpressed Breast Cancer for Methotrexate Delivery

Poly-Lysine Dendritic Nanocarrier to Target Epidermal Growth Factor Receptor Overexpressed Breast Cancer for Methotrexate Delivery

A fourth generation poly-lysine dendritic nanocarrier (P<sub>4</sub>LDN)-based targeted chemotherapy for breast cancer is attempted by incorporating an epidermal growth factor receptor (EGFR)-specific short peptide E2 (ARSHVGYTGAR) and the drug methotrexate (MTX) into a nanocarrier syste...

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Bibliographic Details
Main Authors: Pratibha Narayanan, Anju Krishnan Anitha, Neethu Ajayakumar, Kesavakurup Santhosh Kumar
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Materials
Subjects:
poly-lysine dendritic nanocarrier
targeted drug delivery
breast cancer
methotrexate
epidermal growth factor receptor
in silico approach
Online Access:https://www.mdpi.com/1996-1944/15/3/800

Internet

https://www.mdpi.com/1996-1944/15/3/800

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