Differential expression of 12 histone deacetylase (<it>HDAC</it>) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas

Differential expression of 12 histone deacetylase (<it>HDAC</it>) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas

<p>Abstract</p> <p>Background</p> <p>Glioblastoma is the most lethal primary malignant brain tumor. Although considerable progress has been made in the treatment of this aggressive tumor, the clinical outcome for patients remains poor. Histone deacetylases (HDACs) are r...

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Bibliographic Details
Main Authors: Lucio-Eterovic Agda KB, Cortez Maria AA, Valera Elvis T, Motta Fabio JN, Queiroz Rosane GP, Machado Helio R, Carlotti Carlos G, Neder Luciano, Scrideli Carlos A, Tone Luiz G
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/243

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http://www.biomedcentral.com/1471-2407/8/243

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