Single cell RNA sequencing of human FAPs reveals different functional stages in Duchenne muscular dystrophy

Single cell RNA sequencing of human FAPs reveals different functional stages in Duchenne muscular dystrophy

Background: Duchenne muscular dystrophy is a genetic disease produced by mutations in the dystrophin gene characterized by early onset muscle weakness leading to severe and irreversible disability. Muscle degeneration involves a complex interplay between multiple cell lineages spatially located with...

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Bibliographic Details
Main Authors: Esther Fernández-Simón, Patricia Piñol-Jurado, Rasya Gokul-Nath, Adrienne Unsworth, Jorge Alonso-Pérez, Marianela Schiava, Andres Nascimento, Giorgio Tasca, Rachel Queen, Dan Cox, Xavier Suarez-Calvet, Jordi Díaz-Manera
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
muscle dystrophies
fibro-adipogenic progenitor cells
fibrosis
adipogenesis
single cell RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1399319/full

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https://www.frontiersin.org/articles/10.3389/fcell.2024.1399319/full

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