Neutralizing Potency of Prototype and Omicron RBD mRNA Vaccines Against Omicron Variant

The newly emerged Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains more than 30 mutations on the spike protein, 15 of which are located within the receptor binding domain (RBD). Consequently, Omicron is able to extensively escape existing neutralizing antibodi...

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Bibliographic Details
Main Authors: Jinkai Zang, Yannan Yin, Shiqi Xu, Weihua Qiao, Qiuyue Liu, Dimitri Lavillette, Chao Zhang, Haikun Wang, Zhong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.908478/full