Neutralizing Potency of Prototype and Omicron RBD mRNA Vaccines Against Omicron Variant

Neutralizing Potency of Prototype and Omicron RBD mRNA Vaccines Against Omicron Variant

The newly emerged Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains more than 30 mutations on the spike protein, 15 of which are located within the receptor binding domain (RBD). Consequently, Omicron is able to extensively escape existing neutralizing antibodi...

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Bibliographic Details
Main Authors: Jinkai Zang, Yannan Yin, Shiqi Xu, Weihua Qiao, Qiuyue Liu, Dimitri Lavillette, Chao Zhang, Haikun Wang, Zhong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
omicron variant
receptor-binding domain
mRNA vaccine
neutralizing antibody
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.908478/full

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