Prediction of response to systemic treatment by kinetics of circulating tumor DNA in metastatic pancreatic cancer

Prediction of response to systemic treatment by kinetics of circulating tumor DNA in metastatic pancreatic cancer

IntroductionPretherapeutic detectable circulating tumor DNA (ctDNA) represents a promising prognostic biomarker for predicting relapse and overall survival in patients with metastatic pancreatic cancer. However, the prognostic value of ctDNA dynamics during treatment has not been studied thus far. W...

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Bibliographic Details
Main Authors: Patrick Kirchweger, Alexander Kupferthaler, Jonathan Burghofer, Gerald Webersinke, Emina Jukic, Simon Schwendinger, Helwig Wundsam, Matthias Biebl, Andreas Petzer, Holger Rumpold
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
metastatic pancreatic cancer
predictive marker
response to systemic treatment
liquid biopsy
circulating tumor DNA
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.902177/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.902177/full

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