Isolation, characterization, therapeutic potency, and genomic analysis of a novel bacteriophage vB_KshKPC-M against carbapenemase-producing Klebsiella pneumoniae strains (CRKP) isolated from Ventilator-associated pneumoniae (VAP) infection of COVID-19 patients

Isolation, characterization, therapeutic potency, and genomic analysis of a novel bacteriophage vB_KshKPC-M against carbapenemase-producing Klebsiella pneumoniae strains (CRKP) isolated from Ventilator-associated pneumoniae (VAP) infection of COVID-19 patients

Abstract Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a significant clinical problem, given the lack of therapeutic options. The CRKP strains have emerged as an essential worldwide healthcare issue during the last 10 years. Global expansion of the CRKP has made it a significant pu...

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Bibliographic Details
Main Authors: Mehrdad Mohammadi, Mahmood Saffari, Seyed Davar Siadat, Seyed Hossein Hejazi, Mohammad Shayestehpour, Mitra Motallebi, Milad Eidi
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Klebsiella pneumoniae
Carbapenemase
Bacteriophage
Phage Therapy
Whole genome sequencing
Antibiotic resistance
Online Access:https://doi.org/10.1186/s12941-023-00567-1

Internet

https://doi.org/10.1186/s12941-023-00567-1

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