Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside

<h4>Background</h4> To accelerate the progress towards onchocerciasis elimination, a macrofilaricidal drug that kills the adult parasite is urgently needed. Emodepside has shown macrofilaricidal activity against a variety of nematodes and is currently under clinical development for the t...

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Bibliographic Details
Main Authors: Frauke Assmus, Richard M. Hoglund, Frédéric Monnot, Sabine Specht, Ivan Scandale, Joel Tarning
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912909/?tool=EBI