Melatonin enhances the developmental potential of immature oocytes from older reproductive-aged women by improving mitochondrial function

Melatonin enhances the developmental potential of immature oocytes from older reproductive-aged women by improving mitochondrial function

Aims: To evaluate whether melatonin (MT) supplementation during in vitro maturation (IVM) of human oocytes can reverse the age-related decline in oocyte quality. Main methods: We enrolled 172 patients aged ≥35 years (older reproductive-aged women) and 83 patients aged <35 years (young women) who...

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Bibliographic Details
Main Authors: Dandan Yang, Yaoqin Mu, Jing Wang, Weiwei Zou, Huijuan Zou, Han Yang, Chao Zhang, Yongqi Fan, Heng Zhang, Huan Zhang, Beili Chen, Zhiguo Zhang
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Heliyon
Subjects:
Melatonin
Human oocyte
Older reproductive-aged women
In vitro maturation
Mitochondrial function
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402306574X

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http://www.sciencedirect.com/science/article/pii/S240584402306574X

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