Attenuation mechanism of Brucella melitensis M5-10, implications for vaccine development and differential diagnosis
Brucellosis is a worldwide zoonosis. Vaccination is the most efficient means to prevent and control brucellosis. The current licensed attenuated vaccines for animal use were developed by sequential passage in non-natural hosts that decreased virulence in its original hosts. The attenuation mechanism...
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| Format: | Article |
| Language: | English |
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Higher Education Press
2014-12-01
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| Series: | Frontiers of Agricultural Science and Engineering |
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| Online Access: | http://academic.hep.com.cn/fase/fileup/2095-7505/PDF/2095-7505-2014-4-331.pdf |