Carrier Rate and Mutant Allele Frequency of GM1 Gangliosidosis in Miniature Shiba Inus (Mame Shiba): Population Screening of Breeding Dogs in Japan

Carrier Rate and Mutant Allele Frequency of GM1 Gangliosidosis in Miniature Shiba Inus (Mame Shiba): Population Screening of Breeding Dogs in Japan

GM1 gangliosidosis is a progressive, recessive, autosomal, neurodegenerative, lysosomal storage disorder that affects the brain and multiple systemic organs due to an acid β-galactosidase deficiency encoded by the <i>GLB1</i> gene. This disease occurs in the Shiba Inu breed, which is one...

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Bibliographic Details
Main Authors: Shahnaj Pervin, Md Shafiqul Islam, Yamato Yorisada, Aya Sakai, Shimma Masamune, Akira Yabuki, Tofazzal Md Rakib, Shinichiro Maki, Martia Rani Tacharina, Osamu Yamato
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Animals
Subjects:
carrier rate
mutant allele frequency
Mame Shiba Inu
GM1 gangliosidosis
canine <i>GLB1</i> gene
dog breeding
Online Access:https://www.mdpi.com/2076-2615/12/10/1242

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https://www.mdpi.com/2076-2615/12/10/1242

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