Bioanalytical method development and validation for quantification of amivantamab in rat plasma by LC-MS/MS

Abstract Background Amivantamab is a monoclonal bispecific anti-EGFR-MET antibody used to treat non-small cell lung cancer. There were no published methods using a liquid chromatographic—tandem mass spectrometric approach to develop and validate a feasible, novel, and thoroughly validated method for...

Full description

Bibliographic Details
Main Authors: Pridhvi Krishna Gaddey, Raja Sundararajan
Format: Article
Language:English
Published: SpringerOpen 2024-04-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Online Access:https://doi.org/10.1186/s43094-024-00629-x