Rapid detection of identity-by-descent tracts for mega-scale datasets

Rapid detection of identity-by-descent tracts for mega-scale datasets

Traditional methods to identify genomic regions identical-by-descent (IBD) do not scale well to biobank-level datasets. Here, the authors describe a new IBD algorithm, iLASH, which uses LocAlity-Sensitive Hashing to provide rapid IBD estimation when applied to the PAGE and UK Biobank datasets.

Dades bibliogràfiques
Autors principals: Ruhollah Shemirani, Gillian M. Belbin, Christy L. Avery, Eimear E. Kenny, Christopher R. Gignoux, José Luis Ambite
Format: Article
Idioma:English
Publicat: Nature Portfolio 2021-06-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-021-22910-w

Internet

https://doi.org/10.1038/s41467-021-22910-w

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