Caspase-2 protects against ferroptotic cell death

Caspase-2 protects against ferroptotic cell death

Abstract Caspase-2, one of the most evolutionarily conserved members of the caspase family, is an important regulator of the cellular response to oxidative stress. Given that ferroptosis is suppressed by antioxidant defense pathways, such as that involving selenoenzyme glutathione peroxidase 4 (GPX4...

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Bibliographic Details
Main Authors: Swati Dawar, Mariana C. Benitez, Yoon Lim, Toby A. Dite, Jumana M. Yousef, Niko Thio, Sylvain Garciaz, Thomas D. Jackson, Julia V. Milne, Laura F. Dagley, Wayne A. Phillips, Sharad Kumar, Nicholas J. Clemons
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06560-6

Internet

https://doi.org/10.1038/s41419-024-06560-6

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