H<sub>2</sub>O<sub>2</sub>-Mediated Oxidative Stress Enhances Cystathionine γ-Lyase-Derived H<sub>2</sub>S Synthesis via a Sulfenic Acid Intermediate

H<sub>2</sub>O<sub>2</sub>-Mediated Oxidative Stress Enhances Cystathionine γ-Lyase-Derived H<sub>2</sub>S Synthesis via a Sulfenic Acid Intermediate

Hydrogen sulfide (H<sub>2</sub>S), which is generated mainly by cystathionine <i>γ</i>-lyase (CSE) in the cardiovascular system, plays a pivotal role in a wide range of physiological and pathological processes. However, the regulatory mechanism of the CSE/H<sub>2</su...

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Bibliographic Details
Main Authors: Jun Wang, Guanya Jia, Heng Li, Shasha Yan, Jing Qian, Xin Guo, Ge Li, Haizhen Qi, Zhilong Zhu, Yanjun Wu, Weijuan He, Weining Niu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antioxidants
Subjects:
cystathionine <i>γ</i>-lyase
hydrogen sulfide
hydrogen peroxide
sulfenic acid modification
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/10/9/1488

Internet

https://www.mdpi.com/2076-3921/10/9/1488

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