LPS-induced acute neuroinflammation, involving interleukin-1 beta signaling, leads to proteomic, cellular, and network-level changes in the prefrontal cortex of mice

LPS-induced acute neuroinflammation, involving interleukin-1 beta signaling, leads to proteomic, cellular, and network-level changes in the prefrontal cortex of mice

Neuroinflammation induced by peripheral infections leads to various neuropsychiatric symptoms both in humans and laboratory animals, e.g., to the manifestation of sickness behavior that resembles some features of clinical depression. However, in addition to depression-like behavior, there are other...

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Bibliographic Details
Main Authors: Dániel Mittli, Vanda Tukacs, Lilla Ravasz, Éva Csősz, Tímea Kozma, József Kardos, Gábor Juhász, Katalin Adrienna Kékesi
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Neuroinflammation
Prefrontal cortex
Interleukin-1 beta
Lipopolysaccharide
Patch clamp
Functional connectivity
Online Access:http://www.sciencedirect.com/science/article/pii/S266635462300008X

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http://www.sciencedirect.com/science/article/pii/S266635462300008X

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