DecOT: Bulk Deconvolution With Optimal Transport Loss Using a Single-Cell Reference

Tissues are constituted of heterogeneous cell types. Although single-cell RNA sequencing has paved the way to a deeper understanding of organismal cellular composition, the high cost and technical noise have prevented its wide application. As an alternative, computational deconvolution of bulk tissu...

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Bibliografische gegevens
Hoofdauteurs: Gan Liu, Xiuqin Liu, Liang Ma
Formaat: Artikel
Taal:English
Gepubliceerd in: Frontiers Media S.A. 2022-02-01
Reeks:Frontiers in Genetics
Onderwerpen:
Online toegang:https://www.frontiersin.org/articles/10.3389/fgene.2022.825896/full