Integrated Analyses of Microbiomics and Metabolomics Explore the Effect of Gut Microbiota Transplantation on Diabetes-Associated Cognitive Decline in Zucker Diabetic Fatty Rats

Integrated Analyses of Microbiomics and Metabolomics Explore the Effect of Gut Microbiota Transplantation on Diabetes-Associated Cognitive Decline in Zucker Diabetic Fatty Rats

Diabetes-associated cognitive decline (DACD), one of the complications of type 2 diabetes (T2DM), correlates significantly with the disorder in glycolipid metabolism, insulin/leptin resistance, and accumulation of β-amyloid (Aβ). Although gut microbiota transplantation (GMT), a novel non-invasive ph...

Full description

Bibliographic Details
Main Authors: Tingting Bi, Lijing Zhang, Libin Zhan, Ruiqi Feng, Tian Zhao, Weiming Ren, Tianyi Hang, Wen Zhou, Xiaoguang Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
diabetes-associated cognitive decline
gut microbiota transplantation
microbiota-gut-brain axis
insulin and leptin resistance
β-amyloid
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.913002/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.913002/full

Similar Items