Quercetin induces autophagy-associated death in HL-60 cells through CaMKKβ/AMPK/mTOR signal pathway

Quercetin induces autophagy-associated death in HL-60 cells through CaMKKβ/AMPK/mTOR signal pathway

Acute myeloid leukemia (AML) is one of the most common malignancies of the hematopoietic progenitor cell in adults. Quercetin has gained recognition over the years because of its anti-cancer effect with minimal toxicity. Herein, we aim to investigate the anti-leukemia mechanism of quercetin and to d...

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Bibliographic Details
Main Authors: Xiao Jie, Zhang Ben, Yin Songmei, Xie Shuangfeng, Huang Kezhi, Wang Jieyu, Yang Wenjuan, Liu Hongyun, Zhang Guoyang, Liu Xiaoyan, Li Yiqing, Nie Danian
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-09-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
acute myeloid leukemia
quercetin
autophagy
AMP-activated protein kinase
mammalian rapamycin target protein
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022117

Internet

https://www.sciengine.com/doi/10.3724/abbs.2022117

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