Spotlight on HIV-1 Nef: SERINC3 and SERINC5 Identified as Restriction Factors Antagonized by the Pathogenesis Factor
The Nef protein is an accessory gene product encoded by human immunodeficiency virus types 1 and 2 (HIV-1/-2) and simian immunodeficiency virus (SIV) that boosts virus replication in the infected host and accelerates disease progression. Unlike the HIV-1 accessory proteins Vif, Vpr and Vpu, Nef was,...
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-12-01
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| Series: | Viruses |
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| Online Access: | http://www.mdpi.com/1999-4915/7/12/2970 |