Schistosoma mansoni major egg antigen Smp40: molecular modeling and potential immunoreactivity for anti-pathology vaccine development

The pathogenesis of Schistosoma mansoni infection is largely determined by host T-cell mediated immune responses such as the granulomatous response to tissue deposited eggs and subsequent fibrosis. The major egg antigens have a valuable role in desensitizing the CD4+ Th cells that mediate granuloma...

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Bibliographic Details
Main Authors: Mohamed F Abouel-Nour, Mahmoud Lotfy, Abdelfattah M Attallah, Barbara L Doughty
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2006-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000400004