A point mutation in recC associated with subclonal replacement of carbapenem-resistant Klebsiella pneumoniae ST11 in China

Abstract Adaptation to selective pressures is crucial for clinically important pathogens to establish epidemics, but the underlying evolutionary drivers remain poorly understood. The current epidemic of carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant threat to public health. In...

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Bibliographic Details
Main Authors: Kai Zhou, Chun-Xu Xue, Tingting Xu, Ping Shen, Sha Wei, Kelly L. Wyres, Margaret M. C. Lam, Jinquan Liu, Haoyun Lin, Yunbo Chen, Kathryn E. Holt, the BRICS Working Group, Yonghong Xiao
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38061-z