TRAIL-Expressing Monocyte/Macrophages Are Critical for Reducing Inflammation and Atherosclerosis

TRAIL-Expressing Monocyte/Macrophages Are Critical for Reducing Inflammation and Atherosclerosis

Summary: Circulating tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) levels are reduced in patients with cardiovascular disease, and TRAIL gene deletion in mice exacerbates atherosclerosis and inflammation. How TRAIL protects against atherosclerosis and why levels are reduced i...

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Bibliographic Details
Main Authors: Siân P. Cartland, Scott W. Genner, Gonzalo J. Martínez, Stacy Robertson, Maaike Kockx, Ruby CY. Lin, John F. O'Sullivan, Yen Chin Koay, Pradeep Manuneedhi Cholan, Melkam A. Kebede, Andrew J. Murphy, Seth Masters, Martin R. Bennett, Wendy Jessup, Leonard Kritharides, Carolyn Geczy, Sanjay Patel, Mary M. Kavurma
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218302670

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http://www.sciencedirect.com/science/article/pii/S2589004218302670

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