Spatiotemporal signaling underlies progressive vascular rarefaction in myocardial infarction

Abstract Therapeutic angiogenesis represents a promising avenue to revascularize the ischemic heart. Its limited success is partly due to our poor understanding of the cardiac stroma, specifically mural cells, and their response to ischemic injury. Here, we combine single-cell and positional transcr...

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Bibliographic Details
Main Authors: Lin Wei Tung, Elena Groppa, Hesham Soliman, Bruce Lin, Chihkai Chang, Chun Wai Cheung, Morten Ritso, David Guo, Lucas Rempel, Sarthak Sinha, Christine Eisner, Julyanne Brassard, Kelly McNagny, Jeff Biernaskie, Fabio Rossi
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44227-6