Maternal Herpesviridae infection during pregnancy alters midbrain dopaminergic signatures in adult offspring

Maternal Herpesviridae infection during pregnancy alters midbrain dopaminergic signatures in adult offspring

Background: Motor symptoms of Parkinson's disease (PD) are apparent after a high proportion of dopamine neurons in the substantia nigra have degenerated. The vast majority of PD cases are sporadic, and the underlying pathobiological causes are poorly understood. Adults exhibit great variability...

Full description

Bibliographic Details
Main Authors: Amanda R. Burmeister, Juozas Gordevicius, Emmanuel N. Paul, Christina Houck, Sonia George, Martha L. Escobar Galvis, Qiong Sha, Patrik Brundin, J. Andrew Pospisilik, Karen Racicot, Lena Brundin
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Neurobiology of Disease
Subjects:
Herpes virus
Dopamine neurons
Parkinson's disease
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122001127

Internet

http://www.sciencedirect.com/science/article/pii/S0969996122001127

Similar Items